6MN8
Crystal Structure of Prolyl-tRNA Synthetase from Onchocerca volvulus with bound Halofuginone and nucleotide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Uncharacterized protein | polymer | 505 | 58219.3 | 1 | UniProt (A0A2K6VKP7) Pfam (PF00587) Pfam (PF03129) Pfam (PF09180) | Onchocerca volvulus | |
| 2 | B, C (A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 3 | D (A) | 7-bromo-6-chloro-3-{3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl}quinazolin-4(3H)-one | non-polymer | 414.7 | 1 | Chemie (HFG) | |||
| 4 | E (A) | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 1 | Chemie (ANP) | |||
| 5 | F (A) | ADENOSINE MONOPHOSPHATE | non-polymer | 347.2 | 1 | Chemie (AMP) | |||
| 6 | G (A) | IMIDODIPHOSPHORIC ACID | non-polymer | 177.0 | 1 | Chemie (2PN) | |||
| 7 | H, I, J (A) | GLYCINE | non-polymer | 75.1 | 3 | Chemie (GLY) | |||
| 8 | K, L (A) | SERINE | non-polymer | 105.1 | 2 | Chemie (SER) | |||
| 9 | M (A) | water | water | 18.0 | 165 | Chemie (HOH) |
Sequence modifications
A: 54 - 550 (UniProt: A0A2K6VKP7)
| PDB | External Database | Details |
|---|---|---|
| Met 46 | - | initiating methionine |
| Ala 47 | - | expression tag |
| His 48 | - | expression tag |
| His 49 | - | expression tag |
| His 50 | - | expression tag |
| His 51 | - | expression tag |
| His 52 | - | expression tag |
| His 53 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 58219.3 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 1929.1 | |
| All* | Total formula weight | 60148.4 |
