6MKN
Structure of the Thermus thermophilus 30S ribosomal subunit complexed with an inosine (I34) modified anticodon stem loop (ASL) of Escherichia coli transfer RNA Arginine 2 (TRNAARG2) bound to an mRNA with an CGU-codon in the A-site and paromomycin
Summary for 6MKN
Entry DOI | 10.2210/pdb6mkn/pdb |
Descriptor | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... (25 entities in total) |
Functional Keywords | 2-thiocytidine, inosine, transfer rna, trna, ribosome, 30s, translation, anticodon |
Biological source | Thermus thermophilus HB8 More |
Total number of polymer chains | 23 |
Total formula weight | 788484.90 |
Authors | Cantara, W.A.,DeMirci, H.,Agris, P.F. (deposition date: 2018-09-25, release date: 2019-04-24, Last modification date: 2023-10-11) |
Primary citation | Vangaveti, S.,Cantara, W.A.,Spears, J.L.,DeMirci, H.,Murphy IV, F.V.,Ranganathan, S.V.,Sarachan, K.L.,Agris, P.F. A Structural Basis for Restricted Codon Recognition Mediated by 2-thiocytidine in tRNA Containing a Wobble Position Inosine. J.Mol.Biol., 432:913-929, 2020 Cited by PubMed: 31945376DOI: 10.1016/j.jmb.2019.12.016 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.46 Å) |
Structure validation
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