6MF9

Crystal structure of CGD4-650 with compound BI2536

Summary for 6MF9

• Entry DOI: 10.2210/pdb6mf9/pdb
• Descriptor: ZnKn (C2HC)+Athook+bromo domain protein, Taf250, transcription initiation factor IID, 4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3-methoxy-N-(1-methylpiperidin-4-yl)benzamide (3 entities in total)
• Functional Keywords: cgd4_650, bi2536, structural genomics, structural genomics consortium, sgc, biosynthetic protein
• Biological source: Cryptosporidium parvum (strain Iowa II)
• Total number of polymer chains: 2
• Total formula weight: 38940.35

Authors

Dong, A.,Lin, Y.L.,Hou, D.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.M.,Vedadi, M.,Hui, R.,Structural Genomics Consortium (SGC) (deposition date: 2018-09-10, release date: 2018-10-10, Last modification date: 2023-10-11)

• Primary citation: Dong, A.,Lin, Y.L.,Hou, D.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.M.,Vedadi, M.,Hui, R.,Structural Genomics Consortium (SGC); Crystal structure of CGD4-650 with compound BI2536; to be published,

Experimental method

X-RAY DIFFRACTION (2.037 Å)