6MF9
Crystal structure of CGD4-650 with compound BI2536
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | ZnKn (C2HC)+Athook+bromo domain protein, Taf250, transcription initiation factor IID | polymer | 167 | 18948.5 | 2 | UniProt (Q5CQH9) Pfam (PF00439) | Cryptosporidium parvum (strain Iowa II) | |
| 2 | C, D (A, B) | 4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3-methoxy-N-(1-methylpiperidin-4-yl)benzamide | non-polymer | 521.7 | 2 | Chemie (R78) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 93 | Chemie (HOH) |
Sequence modifications
A, B: 1800 - 1965 (UniProt: Q5CQH9)
| PDB | External Database | Details |
|---|---|---|
| Gly 1799 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 37897.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1043.3 | |
| All* | Total formula weight | 38940.3 |
