6LUR

Human PUF60 UHM domain (thioredoxin fusion) in complex with a small molecule binder

Summary for 6LUR

Entry DOI	10.2210/pdb6lur/pdb
Descriptor	Thioredoxin 1,Poly(U)-binding-splicing factor PUF60, 4-[2-[4-(aminomethyl)phenyl]phenyl]piperazin-2-one (3 entities in total)
Functional Keywords	splicing factor, splicing
Biological source	Escherichia coli (strain K12) More
Total number of polymer chains	8
Total formula weight	199626.26
Authors	Takahashi, M.,Hanzawa, H. (deposition date: 2020-01-30, release date: 2020-04-29, Last modification date: 2023-11-29)
Primary citation	Hanzawa, H.,Shimada, T.,Takahashi, M.,Takahashi, H. Revisiting biomolecular NMR spectroscopy for promoting small-molecule drug discovery. J.Biomol.Nmr, 74:501-508, 2020 Cited by PubMed: 32306215 DOI: 10.1007/s10858-020-00314-0 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation