6LK5
MLKL mutant - T357ES358D
Summary for 6LK5
Entry DOI | 10.2210/pdb6lk5/pdb |
Descriptor | Mixed lineage kinase domain-like protein (2 entities in total) |
Functional Keywords | protein phosphorylation, transferase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 54621.08 |
Authors | Wang, H.Y.,Li, S.,Zhang, Y. (deposition date: 2019-12-18, release date: 2020-12-23, Last modification date: 2023-11-22) |
Primary citation | Zhang, Y.,Liu, J.,Yu, D.,Zhu, X.,Liu, X.,Liao, J.,Li, S.,Wang, H. The MLKL kinase-like domain dimerization is an indispensable step of mammalian MLKL activation in necroptosis signaling. Cell Death Dis, 12:638-638, 2021 Cited by PubMed: 34158471DOI: 10.1038/s41419-021-03859-6 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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