6KYH
Crystal structure of Shank3 NTD-ANK A42K mutant in complex with HRas
Summary for 6KYH
Entry DOI | 10.2210/pdb6kyh/pdb |
Descriptor | SH3 and multiple ankyrin repeat domains protein 3, GTPase HRas, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... (4 entities in total) |
Functional Keywords | shank3, gtpase, synaptic scaffold protein, structural protein-signaling protein complex, structural protein/signaling protein |
Biological source | Mus musculus (Mouse) More |
Total number of polymer chains | 8 |
Total formula weight | 240414.66 |
Authors | |
Primary citation | Cai, Q.,Hosokawa, T.,Zeng, M.,Hayashi, Y.,Zhang, M. Shank3 Binds to and Stabilizes the Active Form of Rap1 and HRas GTPases via Its NTD-ANK Tandem with Distinct Mechanisms. Structure, 28:290-, 2020 Cited by PubMed: 31879129DOI: 10.1016/j.str.2019.11.018 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.3 Å) |
Structure validation
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