6KK7
Structure of thermal-stabilised(M6) human GLP-1 receptor transmembrane domain
Summary for 6KK7
Entry DOI | 10.2210/pdb6kk7/pdb |
Related | 5VEW |
Descriptor | Glucagon-like peptide 1 receptor,Endolysin,Glucagon-like peptide 1 receptor, N-{4-[(R)-(3,3-dimethylcyclobutyl)({6-[4-(trifluoromethyl)-1H-imidazol-1-yl]pyridin-3-yl}amino)methyl]benzene-1-carbonyl}-beta-alanine (2 entities in total) |
Functional Keywords | gpcr, seven-transmembrane, allosteric modulators, diabetes, signaling protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 106129.51 |
Authors | Song, G. (deposition date: 2019-07-23, release date: 2019-11-13, Last modification date: 2023-11-22) |
Primary citation | Xu, Y.,Wang, Y.,Wang, Y.,Liu, K.,Peng, Y.,Yao, D.,Tao, H.,Liu, H.,Song, G. Mutagenesis facilitated crystallization of GLP-1R. Iucrj, 6:996-1006, 2019 Cited by PubMed: 31709055DOI: 10.1107/S2052252519013496 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.1 Å) |
Structure validation
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