6JIG

Crystal structure of GMP reductase C318A from Trypanosoma brucei in complex with guanosine 5'-monophosphate

Summary for 6JIG

Entry DOI	10.2210/pdb6jig/pdb
Descriptor	GMP reductase, GUANOSINE-5'-MONOPHOSPHATE, POTASSIUM ION, ... (4 entities in total)
Functional Keywords	trypanosoma brucei, 5'-monophosphate reductase, guanosine 5'-monophosphate, cystathionine beta synthase motif, oxidoreductase
Biological source	Trypanosoma brucei brucei (strain ILTat1.4)
Total number of polymer chains	1
Total formula weight	54571.72
Authors	Mase, H.,Imamura, A.,Nishimura, S.,Inui, T. (deposition date: 2019-02-21, release date: 2020-02-26, Last modification date: 2023-11-22)
Primary citation	Imamura, A.,Okada, T.,Mase, H.,Otani, T.,Kobayashi, T.,Tamura, M.,Kubata, B.K.,Inoue, K.,Rambo, R.P.,Uchiyama, S.,Ishii, K.,Nishimura, S.,Inui, T. Allosteric regulation accompanied by oligomeric state changes of Trypanosoma brucei GMP reductase through cystathionine-beta-synthase domain. Nat Commun, 11:1837-1837, 2020 Cited by PubMed: 32296055 DOI: 10.1038/s41467-020-15611-3 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.903 Å)

Structure validation