6JIG
Crystal structure of GMP reductase C318A from Trypanosoma brucei in complex with guanosine 5'-monophosphate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | GMP reductase | polymer | 504 | 53806.2 | 1 | UniProt (Q57ZS7) Pfam (PF00478) Pfam (PF00571) | Trypanosoma brucei brucei (strain ILTat1.4) | Guanosine 5'-monophosphate reductase |
| 2 | B, C (A) | GUANOSINE-5'-MONOPHOSPHATE | non-polymer | 363.2 | 2 | Chemie (5GP) | |||
| 3 | D (A) | POTASSIUM ION | non-polymer | 39.1 | 1 | Chemie (K) | |||
| 4 | E (A) | water | water | 18.0 | 95 | Chemie (HOH) |
Sequence modifications
A: 1 - 491 (UniProt: Q57ZS7)
| PDB | External Database | Details |
|---|---|---|
| Ala 318 | Cys 318 | engineered mutation |
| Lys 492 | - | expression tag |
| Leu 493 | - | expression tag |
| Ala 494 | - | expression tag |
| Ala 495 | - | expression tag |
| Ala 496 | - | expression tag |
| Leu 497 | - | expression tag |
| Glu 498 | - | expression tag |
| His 499 | - | expression tag |
| His 500 | - | expression tag |
| His 501 | - | expression tag |
| His 502 | - | expression tag |
| His 503 | - | expression tag |
| His 504 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 53806.2 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 765.5 | |
| All* | Total formula weight | 54571.7 |
