6IY9

Crystal structure of aminoglycoside 7"-phoshotransferase-Ia (APH(7")-Ia/HYG) from Streptomyces hygroscopicus complexed with hygromycin B

Summary for 6IY9

• Entry DOI: 10.2210/pdb6iy9/pdb
• Descriptor: Hygromycin-B 7''-O-kinase, HYGROMYCIN B VARIANT, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, ... (5 entities in total)
• Functional Keywords: kinase, complex, transferase
• Biological source: Streptomyces hygroscopicus
• Total number of polymer chains: 2
• Total formula weight: 78432.47

Authors

Takenoya, M.,Shimamura, T.,Yamanaka, R.,Adachi, Y.,Ito, S.,Sasaki, Y.,Nakamura, A.,Yajima, S. (deposition date: 2018-12-14, release date: 2019-09-11, Last modification date: 2019-11-20)

• Primary citation: Takenoya, M.,Shimamura, T.,Yamanaka, R.,Adachi, Y.,Ito, S.,Sasaki, Y.,Nakamura, A.,Yajima, S.; Structural basis for the substrate recognition of aminoglycoside 7''-phosphotransferase-Ia from Streptomyces hygroscopicus.; Acta Crystallogr.,Sect.F, 75:599-607, 2019; PubMed: 31475927; DOI: 10.1107/S2053230X19011105

Experimental method

X-RAY DIFFRACTION (2.4 Å)