6IY6
Crystal structure of human cytosolic aspartyl-tRNA synthetase (DRS) in complex with glutathion-S transferase (GST) domains from Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 (AIMP2) and glutamyl-prolyl-tRNA synthetase (EPRS)
Summary for 6IY6
Entry DOI | 10.2210/pdb6iy6/pdb |
Descriptor | Aspartate--tRNA ligase, cytoplasmic, Aminoacyl tRNA synthase complex-interacting multifunctional protein 2, Bifunctional glutamate/proline--tRNA ligase, ... (6 entities in total) |
Functional Keywords | aminoacyl-trna transferase glutathion-s transferase domain, translation |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 12 |
Total formula weight | 401385.13 |
Authors | Park, S.H.,Hahn, H.,Han, B.W. (deposition date: 2018-12-13, release date: 2019-09-11, Last modification date: 2023-11-22) |
Primary citation | Hahn, H.,Park, S.H.,Kim, H.J.,Kim, S.,Han, B.W. The DRS-AIMP2-EPRS subcomplex acts as a pivot in the multi-tRNA synthetase complex. Iucrj, 6:958-967, 2019 Cited by PubMed: 31576228DOI: 10.1107/S2052252519010790 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.6 Å) |
Structure validation
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