Crystal structure of GalNAc-T7 with Mn2+

Summary for 6IWQ

DescriptorN-acetylgalactosaminyltransferase 7, MANGANESE (II) ION (3 entities in total)
Functional Keywordspolypeptide n acetylgalactosaminyltransferase activity, transferring glycosyl groups, manganese ion binding, carbohydrate binding, metal ion binding, transferase
Biological sourceHomo sapiens (Human)
Total number of polymer chains6
Total molecular weight413514.89
Yu, C.,Yin, Y.X. (deposition date: 2018-12-06, release date: 2019-02-06)
Primary citation
Yu, C.,Liang, L.,Yin, Y.
Structural basis of carbohydrate transfer activity of UDP-GalNAc: Polypeptide N-acetylgalactosaminyltransferase 7
Biochem. Biophys. Res. Commun., 2019
PubMed: 30685086 (PDB entries with the same primary citation)
DOI: 10.1016/j.bbrc.2019.01.084
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.23939 0.1% 18.4% 3.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 6iwq
no rotation
Molmil generated image of 6iwq
rotated about x axis by 90°
Molmil generated image of 6iwq
rotated about y axis by 90°
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