Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

6IWQ

Crystal structure of GalNAc-T7 with Mn2+

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000139	cellular_component	Golgi membrane
A	0004653	molecular_function	polypeptide N-acetylgalactosaminyltransferase activity
A	0005794	cellular_component	Golgi apparatus
A	0005975	biological_process	carbohydrate metabolic process
A	0006486	biological_process	protein glycosylation
A	0006493	biological_process	protein O-linked glycosylation
A	0016020	cellular_component	membrane
A	0016266	biological_process	O-glycan processing
A	0016740	molecular_function	transferase activity
A	0016757	molecular_function	glycosyltransferase activity
A	0030246	molecular_function	carbohydrate binding
A	0046872	molecular_function	metal ion binding
A	0070062	cellular_component	extracellular exosome
B	0000139	cellular_component	Golgi membrane
B	0004653	molecular_function	polypeptide N-acetylgalactosaminyltransferase activity
B	0005794	cellular_component	Golgi apparatus
B	0005975	biological_process	carbohydrate metabolic process
B	0006486	biological_process	protein glycosylation
B	0006493	biological_process	protein O-linked glycosylation
B	0016020	cellular_component	membrane
B	0016266	biological_process	O-glycan processing
B	0016740	molecular_function	transferase activity
B	0016757	molecular_function	glycosyltransferase activity
B	0030246	molecular_function	carbohydrate binding
B	0046872	molecular_function	metal ion binding
B	0070062	cellular_component	extracellular exosome
C	0000139	cellular_component	Golgi membrane
C	0004653	molecular_function	polypeptide N-acetylgalactosaminyltransferase activity
C	0005794	cellular_component	Golgi apparatus
C	0005975	biological_process	carbohydrate metabolic process
C	0006486	biological_process	protein glycosylation
C	0006493	biological_process	protein O-linked glycosylation
C	0016020	cellular_component	membrane
C	0016266	biological_process	O-glycan processing
C	0016740	molecular_function	transferase activity
C	0016757	molecular_function	glycosyltransferase activity
C	0030246	molecular_function	carbohydrate binding
C	0046872	molecular_function	metal ion binding
C	0070062	cellular_component	extracellular exosome
D	0000139	cellular_component	Golgi membrane
D	0004653	molecular_function	polypeptide N-acetylgalactosaminyltransferase activity
D	0005794	cellular_component	Golgi apparatus
D	0005975	biological_process	carbohydrate metabolic process
D	0006486	biological_process	protein glycosylation
D	0006493	biological_process	protein O-linked glycosylation
D	0016020	cellular_component	membrane
D	0016266	biological_process	O-glycan processing
D	0016740	molecular_function	transferase activity
D	0016757	molecular_function	glycosyltransferase activity
D	0030246	molecular_function	carbohydrate binding
D	0046872	molecular_function	metal ion binding
D	0070062	cellular_component	extracellular exosome
E	0000139	cellular_component	Golgi membrane
E	0004653	molecular_function	polypeptide N-acetylgalactosaminyltransferase activity
E	0005794	cellular_component	Golgi apparatus
E	0005975	biological_process	carbohydrate metabolic process
E	0006486	biological_process	protein glycosylation
E	0006493	biological_process	protein O-linked glycosylation
E	0016020	cellular_component	membrane
E	0016266	biological_process	O-glycan processing
E	0016740	molecular_function	transferase activity
E	0016757	molecular_function	glycosyltransferase activity
E	0030246	molecular_function	carbohydrate binding
E	0046872	molecular_function	metal ion binding
E	0070062	cellular_component	extracellular exosome
F	0000139	cellular_component	Golgi membrane
F	0004653	molecular_function	polypeptide N-acetylgalactosaminyltransferase activity
F	0005794	cellular_component	Golgi apparatus
F	0005975	biological_process	carbohydrate metabolic process
F	0006486	biological_process	protein glycosylation
F	0006493	biological_process	protein O-linked glycosylation
F	0016020	cellular_component	membrane
F	0016266	biological_process	O-glycan processing
F	0016740	molecular_function	transferase activity
F	0016757	molecular_function	glycosyltransferase activity
F	0030246	molecular_function	carbohydrate binding
F	0046872	molecular_function	metal ion binding
F	0070062	cellular_component	extracellular exosome

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	binding site for residue MN A 701

Chain	Residue
A	ASP301
A	HIS303
A	HIS440

site_id	AC2
Number of Residues	3
Details	binding site for residue MN B 701

Chain	Residue
B	ASP301
B	HIS303
B	HIS440

site_id	AC3
Number of Residues	3
Details	binding site for residue MN C 701

Chain	Residue
C	ASP301
C	HIS303
C	HIS440

site_id	AC4
Number of Residues	2
Details	binding site for residue MN D 701

Chain	Residue
D	ASP301
D	HIS440

site_id	AC5
Number of Residues	3
Details	binding site for residue MN E 701

Chain	Residue
E	ASP301
E	HIS303
E	HIS440

site_id	AC6
Number of Residues	3
Details	binding site for residue MN F 701

Chain	Residue
F	ASP301
F	HIS303
F	HIS440

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	42
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
A	ASP247
B	ASP301
B	HIS303
B	TRP412
B	HIS440
B	ARG443
C	ASP247
C	ARG277
C	ASP301
C	HIS303
C	TRP412
A	ARG277
C	HIS440
C	ARG443
D	ASP247
D	ARG277
D	ASP301
D	HIS303
D	TRP412
D	HIS440
D	ARG443
E	ASP247
A	ASP301
E	ARG277
E	ASP301
E	HIS303
E	TRP412
E	HIS440
E	ARG443
F	ASP247
F	ARG277
F	ASP301
F	HIS303
A	HIS303
F	TRP412
F	HIS440
F	ARG443
A	TRP412
A	HIS440
A	ARG443
B	ASP247
B	ARG277

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)