6IWR

Crystal structure of GalNAc-T7 with UDP, GalNAc and Mn2+

Summary for 6IWR

Entry DOI	10.2210/pdb6iwr/pdb
Descriptor	N-acetylgalactosaminyltransferase 7, MANGANESE (II) ION, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
Functional Keywords	polypeptide n acetylgalactosaminyltransferase activity, transferring glycosyl groups, manganese ion binding, carbohydrate binding, metal ion binding, transferase
Biological source	Homo sapiens (Human)
Total number of polymer chains	6
Total formula weight	414747.62
Authors	Yu, C.,Yin, Y.X. (deposition date: 2018-12-06, release date: 2019-02-06, Last modification date: 2020-07-29)
Primary citation	Yu, C.,Liang, L.,Yin, Y. Structural basis of carbohydrate transfer activity of UDP-GalNAc: Polypeptide N-acetylgalactosaminyltransferase 7. Biochem. Biophys. Res. Commun., 510:266-271, 2019 Cited by PubMed: 30685086 DOI: 10.1016/j.bbrc.2019.01.084 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.604 Å)

Structure validation