6IRV

Crystal structure of the human cap-specific adenosine methyltransferase

Summary for 6IRV

Entry DOI	10.2210/pdb6irv/pdb
Descriptor	Phosphorylated CTD-interacting factor 1 (2 entities in total)
Functional Keywords	rna methylation, methyltransferase, m6a, n6-methyladenosine, transferase
Biological source	Homo sapiens (Human)
Total number of polymer chains	2
Total formula weight	118786.05
Authors	Hirano, S.,Nishimasu, H.,Ishitani, R.,Nureki, O. (deposition date: 2018-11-14, release date: 2018-12-05, Last modification date: 2023-11-22)
Primary citation	Akichika, S.,Hirano, S.,Shichino, Y.,Suzuki, T.,Nishimasu, H.,Ishitani, R.,Sugita, A.,Hirose, Y.,Iwasaki, S.,Nureki, O.,Suzuki, T. Cap-specific terminal N 6 -methylation of RNA by an RNA polymerase II-associated methyltransferase. Science, 363:-, 2019 Cited by PubMed: 30467178 DOI: 10.1126/science.aav0080 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation