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6IRV

Crystal structure of the human cap-specific adenosine methyltransferase

Functional Information from GO Data
ChainGOidnamespacecontents
A0016422molecular_functionmRNA (2'-O-methyladenosine-N6-)-methyltransferase activity
A0099122molecular_functionRNA polymerase II C-terminal domain binding
B0016422molecular_functionmRNA (2'-O-methyladenosine-N6-)-methyltransferase activity
B0099122molecular_functionRNA polymerase II C-terminal domain binding
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues8
DetailsBINDING: BINDING => ECO:0000250|UniProtKB:A0A0R4IKJ1
ChainResidueDetails
AARG235
AARG265
AGLU558
ATRP588
BARG235
BARG265
BGLU558
BTRP588

site_idSWS_FT_FI2
Number of Residues4
DetailsBINDING: BINDING => ECO:0000269|PubMed:30467178, ECO:0007744|PDB:6IRW
ChainResidueDetails
AASN553
APHE614
BASN553
BPHE614

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PDB entries from 2024-11-06

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