6IID
Human EXOG-H140A in complex with RNA-DNA chimeric duplex
Summary for 6IID
Entry DOI | 10.2210/pdb6iid/pdb |
Related | 5ZKI 5ZKJ |
Descriptor | Nuclease EXOG, mitochondrial, DNA/RNA (5'-R(P*CP*GP*GP*GP*A)-D(P*T)-R(P*G)-D(P*T)-R(P*CP*AP*CP*G)-3'), DNA (5'-D(*CP*GP*TP*GP*AP*CP*AP*TP*CP*CP*CP*G)-3'), ... (5 entities in total) |
Functional Keywords | enzyme-substrate complex, mitochondrial exonuclease, hydrolase-dna complex, dna binding protein, hydrolase/dna |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 12 |
Total formula weight | 186397.40 |
Authors | Wu, C.C.,Lin, J.L.J.,Yuan, H.S. (deposition date: 2018-10-04, release date: 2019-04-03, Last modification date: 2023-11-22) |
Primary citation | Wu, C.C.,Lin, J.L.J.,Yang-Yen, H.F.,Yuan, H.S. A unique exonuclease ExoG cleaves between RNA and DNA in mitochondrial DNA replication. Nucleic Acids Res., 47:5405-5419, 2019 Cited by PubMed: 30949702DOI: 10.1093/nar/gkz241 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.986 Å) |
Structure validation
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