6I81

Crystal Structure of the second bromodomain of BRD2 in complex with RT56

6I81 の概要

• エントリーDOI: 10.2210/pdb6i81/pdb
• 分子名称: Bromodomain-containing protein 2, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 1,2-ETHANEDIOL, ... (5 entities in total)
• 機能のキーワード: bet, bromodomain, rt56, inhibitor, structural genomics, structural genomics consortium, sgc, transcription
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 13859.42

構造登録者

Picaud, S.,Traquete, R.,Bernardes, G.J.L.,Newman, J.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Filippakopoulos, P.,Structural Genomics Consortium (SGC) (登録日: 2018-11-19, 公開日: 2019-11-27, 最終更新日: 2024-01-24)

• 主引用文献: Picaud, S.,Traquete, R.,Bernardes, G.J.L.,Newman, J.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Filippakopoulos, P.,Structural Genomics Consortium (SGC); Crystal Structure of the second bromodomain of BRD2 in complex with RT56; To Be Published,

実験手法

X-RAY DIFFRACTION (1.74 Å)