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6I2H

Crystal Structure of the Protein-Kinase A catalytic subunit from Cricetulus Griseus in complex with compounds RKp182 and RKp190

Replaces:  6EME
Summary for 6I2H
Entry DOI10.2210/pdb6i2h/pdb
DescriptorcAMP-dependent protein kinase catalytic subunit alpha, UPF0418 protein FAM164A, [2-[[2-(isoquinolin-5-ylsulfonylamino)ethylamino]methyl]phenyl]boronic acid, ... (6 entities in total)
Functional Keywordscomplex, peptidic ligand, transferase
Biological sourceCricetulus griseus (Chinese hamster)
More
Total number of polymer chains2
Total formula weight43768.76
Authors
Mueller, J.M.,Heine, A.,Klebe, G. (deposition date: 2018-11-01, release date: 2019-11-20, Last modification date: 2020-07-29)
Primary citationMueller, J.M.,Kirschner, R.,Heine, A.,Geyer, A.,Klebe, G.
Crystal Structure of the Protein-Kinase A catalytic subunit from Cricetulus Griseus in complex with compounds RKp182 and RKp190
To be published,
Experimental method
X-RAY DIFFRACTION (1.68 Å)
Structure validation

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