6HPR

Crystal structure of cIAP1 RING domain bound to UbcH5B-Ub and a non-covalent Ub

Summary for 6HPR

Entry DOI	10.2210/pdb6hpr/pdb
Descriptor	Baculoviral IAP repeat-containing protein 2, Polyubiquitin-B, Ubiquitin-conjugating enzyme E2 D2, ... (5 entities in total)
Functional Keywords	ubiquitin, e3, ciap1, ubch5b, ubiquitin ligase, ligase
Biological source	Homo sapiens (Human) More
Total number of polymer chains	4
Total formula weight	42062.09
Authors	Patel, A.,Huang, D.T. (deposition date: 2018-09-21, release date: 2018-12-12, Last modification date: 2024-01-24)
Primary citation	Patel, A.,Sibbet, G.J.,Huang, D.T. Structural insights into non-covalent ubiquitin activation of the cIAP1-UbcH5B∼ubiquitin complex. J. Biol. Chem., 294:1240-1249, 2019 Cited by PubMed: 30523153 DOI: 10.1074/jbc.RA118.006045 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation