6HIL
X-ray structure of TEAD1(Y421H mutant) complexed with YAP(wildtype): Molecular and structural characterization of a TEAD mutation at the origin of Sveinsson's chorioretinal atrophy
Summary for 6HIL
Entry DOI | 10.2210/pdb6hil/pdb |
Related | 6HIK |
Descriptor | Transcriptional enhancer factor TEF-1, Transcriptional coactivator YAP1, MYRISTIC ACID, ... (4 entities in total) |
Functional Keywords | other, transcription factor, transcription |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 8 |
Total formula weight | 120409.68 |
Authors | Kallen, J. (deposition date: 2018-08-30, release date: 2019-04-03, Last modification date: 2024-01-17) |
Primary citation | Bokhovchuk, F.,Mesrouze, Y.,Izaac, A.,Meyerhofer, M.,Zimmermann, C.,Fontana, P.,Schmelzle, T.,Erdmann, D.,Furet, P.,Kallen, J.,Chene, P. Molecular and structural characterization of a TEAD mutation at the origin of Sveinsson's chorioretinal atrophy. Febs J., 286:2381-2398, 2019 Cited by PubMed: 30903741DOI: 10.1111/febs.14817 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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