6HIL

X-ray structure of TEAD1(Y421H mutant) complexed with YAP(wildtype): Molecular and structural characterization of a TEAD mutation at the origin of Sveinsson's chorioretinal atrophy

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue MYR A 501

Chain	Residue
A	ALA208
A	VAL293
A	LYS321
A	MET343
A	CYS344
A	MET347

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site_id	AC2
Number of Residues	9
Details	binding site for residue MYR D 501

Chain	Residue
D	LYS321
D	MET343
D	CYS344
D	LEU367
D	PHE370
D	ILE372
D	PHE224
D	VAL293
D	THR309

---

site_id	AC3
Number of Residues	8
Details	binding site for residue MYR B 501

Chain	Residue
B	ALA208
B	VAL293
B	LYS321
B	MET343
B	CYS344
B	MET347
B	LEU367
B	PHE392

---

site_id	AC4
Number of Residues	9
Details	binding site for residue MYR C 501

Chain	Residue
C	ALA208
C	VAL293
C	LYS321
C	MET343
C	CYS344
C	MET347
C	LEU367
C	ILE372
C	PHE392

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Modified residue: {"description":"N6-lactoyllysine","evidences":[{"source":"PubMed","id":"38512451","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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