6HC8

Factor Inhibiting HIF (FIH) in complex with zinc, NOG and TRPA1 (313-339)

Summary for 6HC8

• Entry DOI: 10.2210/pdb6hc8/pdb
• Descriptor: Hypoxia-inducible factor 1-alpha inhibitor, Transient receptor potential cation channel subfamily A member 1, ZINC ION, ... (7 entities in total)
• Functional Keywords: non-heme, dioxygenase, oxygenase, metal-binding, transcription, dsbh, facial triad, asparaginyl/aspartyl hydroxylase, signaling, ard, beta-hydroxylation, activator-inhibitor, oxidoreductase-peptide complex, oxidoreductase ankyrin, channel, protein binding, ion channel, trpa channel, membrane protein, gene regulation
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 44068.62

Authors

Leissing, T.M.,Clifton, I.J.,Saward, B.G.,Lu, X.,Hopkinson, R.J.,Schofield, C.J. (deposition date: 2018-08-14, release date: 2019-08-28, Last modification date: 2024-01-17)

• Primary citation: Leissing, T.M.,Clifton, I.J.,Saward, B.G.,Lu, X.,Hopkinson, R.J.,Schofield, C.J.; Factor Inhibiting HIF (FIH) in complex with zinc, NOG and TRPA1 (313-339); To Be Published,

Experimental method

X-RAY DIFFRACTION (1.9 Å)