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6HC8

Factor Inhibiting HIF (FIH) in complex with zinc, NOG and TRPA1 (313-339)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Hypoxia-inducible factor 1-alpha inhibitorpolymer35040415.41UniProt (Q9NWT6)
Pfam (PF13621)
Homo sapiens (Human)Factor inhibiting HIF-1,FIH-1,Hypoxia-inducible factor asparagine hydroxylase
2B
(E)
Transient receptor potential cation channel subfamily A member 1polymer273068.41UniProt (O75762)
Pfam (PF00023)
Homo sapiensAnkyrin-like with transmembrane domains protein 1,Transformation-sensitive protein p120
3C
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
4D
(A)
N-OXALYLGLYCINEnon-polymer147.11Chemie (OGA)
5E
(A)
SULFATE IONnon-polymer96.11Chemie (SO4)
6F, G, H
(A)
GLYCEROLnon-polymer92.13Chemie (GOL)
7I, J
(A, E)
waterwater18.0147Chemie (HOH)
Sequence modifications
A: 1 - 349 (UniProt: Q9NWT6)
PDBExternal DatabaseDetails
Ser 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight43483.8
Non-Polymers*Number of molecules6
Total formula weight584.8
All*Total formula weight44068.6
*Water molecules are not included.

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PDB entries from 2024-11-06

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