6H2V

Crystal structure of human METTL5-TRMT112 complex, the 18S rRNA m6A1832 methyltransferase at 2.5A resolution

6H2V の概要

• エントリーDOI: 10.2210/pdb6h2v/pdb
• 分子名称: Methyltransferase-like protein 5, Multifunctional methyltransferase subunit TRM112-like protein, S-ADENOSYLMETHIONINE, ... (8 entities in total)
• 機能のキーワード: rrna maturation, methyltransferase, translation, ribosome synthesis, transferase
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 79685.67

構造登録者

van Tran, N.,Graille, M. (登録日: 2018-07-16, 公開日: 2019-07-31, 最終更新日: 2024-01-17)

• 主引用文献: van Tran, N.,Ernst, F.G.M.,Hawley, B.R.,Zorbas, C.,Ulryck, N.,Hackert, P.,Bohnsack, K.E.,Bohnsack, M.T.,Jaffrey, S.R.,Graille, M.,Lafontaine, D.L.J.; The human 18S rRNA m6A methyltransferase METTL5 is stabilized by TRMT112.; Nucleic Acids Res., 47:7719-7733, 2019; PubMed: 31328227; DOI: 10.1093/nar/gkz619

実験手法

X-RAY DIFFRACTION (2.49 Å)