6H0B
Crystal structure of the human GalNAc-T4 in complex with UDP, manganese and the diglycopeptide 6.
Summary for 6H0B
Entry DOI | 10.2210/pdb6h0b/pdb |
Descriptor | Polypeptide N-acetylgalactosaminyltransferase 4, ALA-THR-GLY-ALA-GLY-ALA-GLY-ALA-GLY-THR-THR-PRO-GLY-PRO-GLY, 1,2-ETHANEDIOL, ... (8 entities in total) |
Functional Keywords | galnac-ts, galnac-t4, short-range glycosylation preference, long-range glycosylation preference, (glyco)peptides, std-nmr, molecular dynamics, enzyme kinetics, transferase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 137938.85 |
Authors | de las Rivas, M.,Daniel, E.J.P.,Coelho, H.,Lira-Navarrete, E.,Raich, L.,Companon, I.,Diniz, A.,Lagartera, L.,Jimenez-Barbero, J.,Clausen, H.,Rovira, C.,Marcelo, F.,Corzana, F.,Gerken, T.A.,Hurtado-Guerrero, R. (deposition date: 2018-07-08, release date: 2018-10-10, Last modification date: 2024-01-17) |
Primary citation | de Las Rivas, M.,Paul Daniel, E.J.,Coelho, H.,Lira-Navarrete, E.,Raich, L.,Companon, I.,Diniz, A.,Lagartera, L.,Jimenez-Barbero, J.,Clausen, H.,Rovira, C.,Marcelo, F.,Corzana, F.,Gerken, T.A.,Hurtado-Guerrero, R. Structural and Mechanistic Insights into the Catalytic-Domain-Mediated Short-Range Glycosylation Preferences of GalNAc-T4. ACS Cent Sci, 4:1274-1290, 2018 Cited by PubMed: 30276263DOI: 10.1021/acscentsci.8b00488 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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