6GR8

Human AURKC INCENP complex bound to BRD-7880

Summary for 6GR8

• Entry DOI: 10.2210/pdb6gr8/pdb
• Descriptor: Aurora kinase C, Inner centromere protein, 1-[(2~{R},3~{S})-2-[[1,3-benzodioxol-5-ylmethyl(methyl)amino]methyl]-3-methyl-6-oxidanylidene-5-[(2~{S})-1-oxidanylpropan-2-yl]-3,4-dihydro-2~{H}-1,5-benzoxazocin-8-yl]-3-(4-methoxyphenyl)urea, ... (4 entities in total)
• Functional Keywords: kinase, structural genomics consortium, sgc, transferase
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 41060.17

Authors

Abdul Azeez, K.R.,Sorrell, F.J.,von Delft, F.,Bountra, C.,Knapp, S.,Edwards, A.M.,Arrowsmith, C.,Elkins, J.M. (deposition date: 2018-06-10, release date: 2019-05-15, Last modification date: 2024-10-23)

• Primary citation: Abdul Azeez, K.R.,Elkins, J.M.; AURKC INCENP complex bound to BRD-7880; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.75 Å)