6GR8
Human AURKC INCENP complex bound to BRD-7880
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Aurora kinase C | polymer | 274 | 32167.1 | 1 | UniProt (Q9UQB9) Pfam (PF00069) In PDB | Homo sapiens (Human) | Aurora 3,Aurora/IPL1-related kinase 3,Aurora-related kinase 3,Aurora/IPL1/Eg2 protein 2,Serine/threonine-protein kinase 13,Serine/threonine-protein kinase aurora-C |
| 2 | B | Inner centromere protein | polymer | 70 | 8302.4 | 1 | UniProt (Q9NQS7) Pfam (PF03941) In PDB | Homo sapiens (Human) | |
| 3 | A | 1-[(2~{R},3~{S})-2-[[1,3-benzodioxol-5-ylmethyl(methyl)amino]methyl]-3-methyl-6-oxidanylidene-5-[(2~{S})-1-oxidanylpropan-2-yl]-3,4-dihydro-2~{H}-1,5-benzoxazocin-8-yl]-3-(4-methoxyphenyl)urea | non-polymer | 590.7 | 1 | Chemie (F8Z) | |||
| 4 | water | water | 18.0 | 311 | Chemie (HOH) |
Sequence modifications
A: 36 - 305 (UniProt: Q9UQB9)
B: 835 - 903 (UniProt: Q9NQS7)
| PDB | External Database | Details |
|---|---|---|
| Gly 32 | - | expression tag |
| Ala 33 | - | expression tag |
| Asn 34 | - | expression tag |
| Ser 35 | - | expression tag |
| Asp 136 | Glu 136 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Met 834 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 40469.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 590.7 | |
| All* | Total formula weight | 41060.2 |
