6GOP

Yeast 20S Proteasome in complex with Homosalinosporamide A

Summary for 6GOP

• Entry DOI: 10.2210/pdb6gop/pdb
• Related: 2FAK 5CZ4
• Descriptor: Proteasome subunit alpha type-2, Proteasome subunit beta type-4, Proteasome subunit beta type-5, ... (18 entities in total)
• Functional Keywords: hydrolase-hydrolase inhibitor complex, natural product, proteasome, inhibitor, binding analysis, hydrolase
• Biological source: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast); More
• Total number of polymer chains: 28
• Total formula weight: 733341.63

Authors

Groll, M.,Romo, D. (deposition date: 2018-06-01, release date: 2018-08-01, Last modification date: 2024-01-17)

• Primary citation: Groll, M.,Nguyen, H.,Vellalath, S.,Romo, D.; (-)-Homosalinosporamide A and Its Mode of Proteasome Inhibition: An X-ray Crystallographic Study.; Mar Drugs, 16:-, 2018; PubMed: 30029468; DOI: 10.3390/md16070240

Experimental method

X-RAY DIFFRACTION (2.9 Å)