Yeast 20S proteasome at 2.3 A resolution

Summary for 5CZ4

DescriptorProteasome subunit alpha type-2, Proteasome subunit alpha type-3, Proteasome subunit alpha type-4, ... (17 entities in total)
Functional Keywordshydrolase-hydrolase complex, ubiquitin-degradation system, proteasome, ntn-hydrolase, thr-protease, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Cellular locationCytoplasm P23639 P23638 P40303 P32379 P40302 P21242 P21243 P25043 P25451 P22141 P30656 P23724 P30657 P38624
Total number of polymer chains28
Total molecular weight731316.12
Huber, E.M.,Groll, M. (deposition date: 2015-07-31, release date: 2016-03-23)
Primary citation
Huber, E.M.,Heinemeyer, W.,Li, X.,Arendt, C.S.,Hochstrasser, M.,Groll, M.
A unified mechanism for proteolysis and autocatalytic activation in the 20S proteasome.
Nat Commun, 7:10900-10900, 2016
PubMed: 26964885 (PDB entries with the same primary citation)
DOI: 10.1038/ncomms10900
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.23220.3%4.1%5.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report