6GM9

Human Carbonic Anhydrase II in complex with 4-Methylbenzenesulfonamide

Summary for 6GM9

• Entry DOI: 10.2210/pdb6gm9/pdb
• Related: 6GDC
• Descriptor: Carbonic anhydrase 2, ZINC ION, MERCURY (II) ION, ... (8 entities in total)
• Functional Keywords: lyase, inhibitor, complex, co2-conversion
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 31277.19

Authors

Gloeckner, S.,Heine, A.,Klebe, G. (deposition date: 2018-05-24, release date: 2019-06-19, Last modification date: 2024-01-17)

• Primary citation: Glockner, S.,Ngo, K.,Sager, C.P.,Hufner-Wulsdorf, T.,Heine, A.,Klebe, G.; Conformational Changes in Alkyl Chains Determine the Thermodynamic and Kinetic Binding Profiles of Carbonic Anhydrase Inhibitors.; Acs Chem.Biol., 15:675-685, 2020; PubMed: 32027480; DOI: 10.1021/acschembio.9b00895

Experimental method

X-RAY DIFFRACTION (1.089 Å)