6GJK

A degradation product of PD 404182 (P2742) bound to Histone Deacetylase-like Amidohydrolase

Summary for 6GJK

Entry DOI	10.2210/pdb6gjk/pdb
Descriptor	Histone deacetylase-like amidohydrolase, ZINC ION, POTASSIUM ION, ... (9 entities in total)
Functional Keywords	hdah, hdac, p2742, pd 404182, histone deacetylase-like amidohydrolase, histone deacetylase, covalent modification, hydrolase
Biological source	Alcaligenaceae bacterium FB188
Total number of polymer chains	2
Total formula weight	82928.75
Authors	Kraemer, A.,Meyer-Almes, F.J. (deposition date: 2018-05-16, release date: 2019-01-16, Last modification date: 2024-01-17)
Primary citation	Muth, M.,Jansch, N.,Kopranovic, A.,Kramer, A.,Wossner, N.,Jung, M.,Kirschhofer, F.,Meyer-Almes, F.J. Covalent inhibition of histone deacetylase 8 by 3,4-dihydro-2H-pyrimido[1,2-c][1,3]benzothiazin-6-imine. Biochim Biophys Acta Gen Subj, 1863:577-585, 2019 Cited by PubMed: 30611847 DOI: 10.1016/j.bbagen.2019.01.001 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.47 Å)

Structure validation