6GIV

Structure of GluA2-N775S ligand-binding domain (S1S2J) in complex with glutamate and Rubidium Bromide at 1.75 A resolution

Summary for 6GIV

DescriptorGlutamate receptor 2, GLUTAMIC ACID, SULFATE ION, ... (6 entities in total)
Functional Keywordsionotropic glutamate receptor, glua2-n775s ligand-binding domain, agonist, membrane protein, bromide ions
Biological sourceRattus norvegicus (Norway Rat)
Total number of polymer chains1
Total molecular weight29851.09
Authors
Venskutonyte, R.,Frydenvang, K.,Kastrup, J.S. (deposition date: 2018-05-15, release date: 2019-05-15)
Primary citation
Dawe, G.B.,Kadir, M.F.,Venskutonyte, R.,Perozzo, A.M.,Yan, Y.,Alexander, R.P.D.,Navarrete, C.,Santander, E.A.,Arsenault, M.,Fuentes, C.,Aurousseau, M.R.P.,Frydenvang, K.,Barrera, N.P.,Kastrup, J.S.,Edwardson, J.M.,Bowie, D.
Nanoscale Mobility of the Apo State and TARP Stoichiometry Dictate the Gating Behavior of Alternatively Spliced AMPA Receptors.
Neuron, 2019
PubMed: 31053408 (PDB entries with the same primary citation)
DOI: 10.1016/j.neuron.2019.03.046
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.75 Å)
?

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.19910 0.5% 0.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 6giv
no rotation
Molmil generated image of 6giv
rotated about x axis by 90°
Molmil generated image of 6giv
rotated about y axis by 90°

More Biological unit images

Molmil generated image of 6giv
no rotation
Molmil generated image of 6giv
rotated about x axis by 90°
Molmil generated image of 6giv
rotated about y axis by 90°
(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (6giv.pdb1.gz [183 KB])