Structure of GluA2-N775S ligand-binding domain (S1S2J) in complex with glutamate and Rubidium Bromide at 1.75 A resolution

Summary for 6GIV

DescriptorGlutamate receptor 2, GLUTAMIC ACID, SULFATE ION, ... (6 entities in total)
Functional Keywordsionotropic glutamate receptor, glua2-n775s ligand-binding domain, agonist, membrane protein, bromide ions
Biological sourceRattus norvegicus (Norway Rat)
Total number of polymer chains1
Total molecular weight29851.09
Venskutonyte, R.,Frydenvang, K.,Kastrup, J.S. (deposition date: 2018-05-15, release date: 2019-05-15, Last modification date: 2019-06-19)
Primary citation
Dawe, G.B.,Kadir, M.F.,Venskutonyte, R.,Perozzo, A.M.,Yan, Y.,Alexander, R.P.D.,Navarrete, C.,Santander, E.A.,Arsenault, M.,Fuentes, C.,Aurousseau, M.R.P.,Frydenvang, K.,Barrera, N.P.,Kastrup, J.S.,Edwardson, J.M.,Bowie, D.
Nanoscale Mobility of the Apo State and TARP Stoichiometry Dictate the Gating Behavior of Alternatively Spliced AMPA Receptors.
Neuron, 102:976-, 2019
PubMed: 31053408 (PDB entries with the same primary citation)
DOI: 10.1016/j.neuron.2019.03.046
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.19910 0.5% 0.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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