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6GIV

Structure of GluA2-N775S ligand-binding domain (S1S2J) in complex with glutamate and Rubidium Bromide at 1.75 A resolution

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Glutamate receptor 2polymer26429251.71UniProt (P19491)
Pfam (PF10613)
Pfam (PF00060)
Rattus norvegicus (Norway Rat)GluR-2,AMPA-selective glutamate receptor 2,GluR-B,GluR-K2,Glutamate receptor ionotropic,AMPA 2,GluA2
2B
(A)
GLUTAMIC ACIDnon-polymer147.11Chemie (GLU)
3C
(A)
SULFATE IONnon-polymer96.11Chemie (SO4)
4D, E, F
(A)
GLYCEROLnon-polymer92.13Chemie (GOL)
5G
(A)
BROMIDE IONnon-polymer79.91Chemie (BR)
6H
(A)
waterwater18.0264Chemie (HOH)
Sequence modifications
A: 3 - 117 (UniProt: P19491)
PDBExternal DatabaseDetails
Gly 1-expression tag
Ala 2-expression tag
A: 120 - 264 (UniProt: P19491)
PDBExternal DatabaseDetails
Gly 118-linker
Thr 119-linker
Ser 242Asn 775engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight29251.7
Non-Polymers*Number of molecules6
Total formula weight599.4
All*Total formula weight29851.1
*Water molecules are not included.

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PDB entries from 2025-07-16

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