6GEI

TEAD4 (216-434);E263A+Y429F COMPLEXED WITH YAP PEPTIDE (60- 100);S94A AND MYRISTOATE (COVALENTLY BOUND TO LYS344, NOT CYS367!) AT 1.65A (P41212 CRYSTAL FORM); MYRISTOYLATION WAS DONE BY ADDING MYR-COA

Summary for 6GEI

• Entry DOI: 10.2210/pdb6gei/pdb
• Related: 6GE3 6GE4 6GE5 6GE6 6GEC 6GEE 6GEG
• Descriptor: Transcriptional enhancer factor TEF-3, Transcriptional coactivator YAP1, MYRISTIC ACID, ... (5 entities in total)
• Functional Keywords: other, transcription
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 30410.38

Authors

Kallen, J. (deposition date: 2018-04-26, release date: 2018-09-19, Last modification date: 2024-01-17)

• Primary citation: Mesrouze, Y.,Bokhovchuk, F.,Izaac, A.,Meyerhofer, M.,Zimmermann, C.,Fontana, P.,Schmelzle, T.,Erdmann, D.,Furet, P.,Kallen, J.,Chene, P.; Adaptation of the bound intrinsically disordered protein YAP to mutations at the YAP:TEAD interface.; Protein Sci., 27:1810-1820, 2018; PubMed: 30058229; DOI: 10.1002/pro.3493

Experimental method

X-RAY DIFFRACTION (1.65 Å)