6GEI
TEAD4 (216-434);E263A+Y429F COMPLEXED WITH YAP PEPTIDE (60- 100);S94A AND MYRISTOATE (COVALENTLY BOUND TO LYS344, NOT CYS367!) AT 1.65A (P41212 CRYSTAL FORM); MYRISTOYLATION WAS DONE BY ADDING MYR-COA
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue MYR A 501 |
| Chain | Residue |
| A | VAL316 |
| A | THR332 |
| A | LYS344 |
| A | LEU366 |
| A | CYS367 |
| A | LEU390 |
| A | ILE395 |
| site_id | AC2 |
| Number of Residues | 12 |
| Details | binding site for residue PO4 A 502 |
| Chain | Residue |
| A | ILE250 |
| A | GLY251 |
| A | GLN252 |
| A | SER253 |
| A | SER254 |
| A | HIS426 |
| A | HOH618 |
| A | HOH630 |
| A | HOH635 |
| A | HOH707 |
| A | GLY216 |
| A | HIS249 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine; by LATS1 and LATS2 => ECO:0000269|PubMed:17974916, ECO:0000269|PubMed:18158288, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| L | SER61 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphothreonine => ECO:0007744|PubMed:20068231 |
| Chain | Residue | Details |
| L | THR63 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | MOD_RES: N6-lactoyllysine => ECO:0000269|PubMed:38512451 |
| Chain | Residue | Details |
| L | LYS90 |
