6FZH
Crystal structure of a streptococcal dehydrogenase at 1.5 Angstroem resolution
Summary for 6FZH
Entry DOI | 10.2210/pdb6fzh/pdb |
Descriptor | Glyceraldehyde-3-phosphate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, GLYCEROL, ... (5 entities in total) |
Functional Keywords | streptococcus pyogenes, gapdh, nad, dehydrogenase, oxidoreductase, anacardic acid, curcumin, complement, c5a, c3a, c3 |
Biological source | Streptococcus pyogenes MGAS8232 |
Total number of polymer chains | 2 |
Total formula weight | 73674.52 |
Authors | Gomez, S.,Querol-Garcia, J.,Sanchez-Barron, G.,Subias, M.,Gonzalez-Alsina, A.,Melchor-Tafur, C.,Franco-Hidalgo, V.,Alberti, S.,Rodriguez de Cordoba, S.,Fernandez, F.J.,Vega, M.C. (deposition date: 2018-03-14, release date: 2019-03-27, Last modification date: 2024-01-17) |
Primary citation | Gomez, S.,Querol-Garcia, J.,Sanchez-Barron, G.,Subias, M.,Gonzalez-Alsina, A.,Franco-Hidalgo, V.,Alberti, S.,Rodriguez de Cordoba, S.,Fernandez, F.J.,Vega, M.C. The Antimicrobials Anacardic Acid and Curcumin Are Not-Competitive Inhibitors of Gram-Positive Bacterial Pathogenic Glyceraldehyde-3-Phosphate Dehydrogenase by a Mechanism Unrelated to Human C5a Anaphylatoxin Binding. Front Microbiol, 10:326-326, 2019 Cited by PubMed: 30863383DOI: 10.3389/fmicb.2019.00326 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
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