Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004365 | molecular_function | glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006006 | biological_process | glucose metabolic process |
| A | 0006096 | biological_process | glycolytic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| A | 0050661 | molecular_function | NADP binding |
| A | 0051287 | molecular_function | NAD binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004365 | molecular_function | glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006006 | biological_process | glucose metabolic process |
| B | 0006096 | biological_process | glycolytic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| B | 0050661 | molecular_function | NADP binding |
| B | 0051287 | molecular_function | NAD binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 35 |
| Details | binding site for residue NAD A 401 |
| Chain | Residue |
| A | ASN8 |
| A | THR97 |
| A | GLY98 |
| A | PHE99 |
| A | PHE100 |
| A | THR121 |
| A | ALA122 |
| A | CYS152 |
| A | PRO191 |
| A | ASN316 |
| A | TYR320 |
| A | GLY9 |
| A | HOH516 |
| A | HOH596 |
| A | HOH597 |
| A | HOH598 |
| A | HOH628 |
| A | HOH643 |
| A | HOH661 |
| A | HOH677 |
| A | HOH703 |
| A | HOH704 |
| A | GLY11 |
| A | HOH708 |
| A | HOH709 |
| A | HOH714 |
| A | HOH716 |
| A | HOH739 |
| A | HOH742 |
| A | ARG12 |
| A | ILE13 |
| A | ASP34 |
| A | LEU35 |
| A | ARG78 |
| A | ALA96 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 402 |
| Chain | Residue |
| A | ASN39 |
| A | HIS43 |
| A | LYS46 |
| A | TYR47 |
| A | HOH523 |
| A | HOH705 |
| B | ASP276 |
| site_id | AC3 |
| Number of Residues | 34 |
| Details | binding site for residue NAD B 401 |
| Chain | Residue |
| B | GLY9 |
| B | GLY11 |
| B | ARG12 |
| B | ILE13 |
| B | ASP34 |
| B | LEU35 |
| B | ARG78 |
| B | ALA96 |
| B | THR97 |
| B | GLY98 |
| B | PHE99 |
| B | PHE100 |
| B | THR121 |
| B | ALA122 |
| B | PRO191 |
| B | ASN316 |
| B | TYR320 |
| B | HOH596 |
| B | HOH601 |
| B | HOH606 |
| B | HOH623 |
| B | HOH627 |
| B | HOH630 |
| B | HOH645 |
| B | HOH654 |
| B | HOH673 |
| B | HOH680 |
| B | HOH682 |
| B | HOH721 |
| B | HOH725 |
| B | HOH733 |
| B | HOH759 |
| B | HOH760 |
| B | HOH896 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue PEG B 402 |
| Chain | Residue |
| B | ASN134 |
| B | HIS137 |
| B | ASN268 |
| B | HOH514 |
| B | HOH542 |
| B | HOH863 |
| site_id | AC5 |
| Number of Residues | 11 |
| Details | binding site for residue GOL B 403 |
| Chain | Residue |
| B | PRO123 |
| B | SER151 |
| B | THR154 |
| B | GLY213 |
| B | ALA214 |
| B | ALA217 |
| B | HOH502 |
| B | HOH505 |
| B | HOH507 |
| B | HOH648 |
| B | HOH842 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue GOL B 404 |
| Chain | Residue |
| A | THR295 |
| B | ARG198 |
| B | ASN210 |
| B | HOH605 |
| B | HOH634 |
Functional Information from PROSITE/UniProt
| site_id | PS00071 |
| Number of Residues | 8 |
| Details | GAPDH Glyceraldehyde 3-phosphate dehydrogenase active site. ASCTTNcL |
| Chain | Residue | Details |
| A | ALA150-LEU157 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Nucleophile","evidences":[{"source":"UniProtKB","id":"P00362","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 22 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"P00362","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Site: {"description":"Activates thiol group during catalysis","evidences":[{"source":"UniProtKB","id":"Q6GIL8","evidenceCode":"ECO:0000250"}]} |
