6FYH
Disulfide between ubiquitin G76C and the E3 HECT ligase Huwe1
Summary for 6FYH
Entry DOI | 10.2210/pdb6fyh/pdb |
Descriptor | E3 ubiquitin-protein ligase HUWE1, Polyubiquitin-B, SULFATE ION, ... (5 entities in total) |
Functional Keywords | huwe1 hect, ubiquitin transfer, thioester, ligase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 23406.44 |
Authors | Jaeckl, M.,Hartmann, M.D.,Wiesner, S. (deposition date: 2018-03-12, release date: 2018-07-11, Last modification date: 2024-01-17) |
Primary citation | Jackl, M.,Stollmaier, C.,Strohaker, T.,Hyz, K.,Maspero, E.,Polo, S.,Wiesner, S. beta-Sheet Augmentation Is a Conserved Mechanism of Priming HECT E3 Ligases for Ubiquitin Ligation. J. Mol. Biol., 430:3218-3233, 2018 Cited by PubMed: 29964046DOI: 10.1016/j.jmb.2018.06.044 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.906 Å) |
Structure validation
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