6FY2

Crystal structure of a V2p-reactive RV144 vaccine-like antibody, CAP228-16H, in complex with a heterologous CAP225 V1V2

Summary for 6FY2

Entry DOI	10.2210/pdb6fy2/pdb
Descriptor	CAP228-16H Heavy Chain, CAP228-16H Light Chain, CAP225 Scaffolded V1V2, ... (6 entities in total)
Functional Keywords	fab, hiv-1 envelope v1v2, immune system
Biological source	Homo sapiens More
Total number of polymer chains	6
Total formula weight	126903.04
Authors	Wibmer, C.K.,Moore, P.L.,Morris, L. (deposition date: 2018-03-10, release date: 2018-09-05, Last modification date: 2018-11-07)
Primary citation	Wibmer, C.K.,Richardson, S.I.,Yolitz, J.,Cicala, C.,Arthos, J.,Moore, P.L.,Morris, L. Common helical V1V2 conformations of HIV-1 Envelope expose the alpha 4 beta 7 binding site on intact virions. Nat Commun, 9:4489-4489, 2018 Cited by PubMed: 30367034 DOI: 10.1038/s41467-018-06794-x PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.301 Å)

Structure validation