Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

6FWH

Acanthamoeba IGPD in complex with R-C348 to 1.7A resolution

Summary for 6FWH
Entry DOI10.2210/pdb6fwh/pdb
DescriptorImidazoleglycerol-phosphate dehydratase, MANGANESE (II) ION, [(2R)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl]phosphonic acid, ... (5 entities in total)
Functional Keywordsinhibitor, histidine biosynthesis, acanthamoeba, lyase
Biological sourceAcanthamoeba castellanii (Amoeba)
Total number of polymer chains12
Total formula weight261065.30
Authors
Roberts, C.W.,Bisson, C.,Baker, P.J. (deposition date: 2018-03-06, release date: 2018-07-18, Last modification date: 2024-01-17)
Primary citationRice, C.A.,Campbell, S.J.,Bisson, C.,Owen, H.J.,Sedelnikova, S.E.,Baker, P.J.,Rice, D.W.,Henriquez, F.L.,Roberts, C.W.
Structural and functional studies of histidine biosynthesis in Acanthamoeba spp. demonstrates a novel molecular arrangement and target for antimicrobials.
PLoS ONE, 13:e0198827-e0198827, 2018
Cited by
PubMed: 29969448
DOI: 10.1371/journal.pone.0198827
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.79 Å)
Structure validation

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon