6FI8
Crystal structure of the IS608 transposase in complex with left end 29-mer DNA hairpin and a 6-mer DNA representing the intact target site: pre-cleavage target capture complex
Summary for 6FI8
Entry DOI | 10.2210/pdb6fi8/pdb |
Descriptor | Putative transposase, DNA 29-MER (LE29), DNA 6-MER (T6'), ... (5 entities in total) |
Functional Keywords | dna-binding protein, protein-dna complex, huh motif, dna stem loop, transposition, tnpa transposase, target capture complex, ishp608, dna binding protein |
Biological source | Helicobacter pylori (Campylobacter pylori) More |
Total number of polymer chains | 12 |
Total formula weight | 117018.87 |
Authors | Morero, N.R.,Barabas, O. (deposition date: 2018-01-17, release date: 2018-03-28, Last modification date: 2024-01-17) |
Primary citation | Morero, N.R.,Zuliani, C.,Kumar, B.,Bebel, A.,Okamoto, S.,Guynet, C.,Hickman, A.B.,Chandler, M.,Dyda, F.,Barabas, O. Targeting IS608 transposon integration to highly specific sequences by structure-based transposon engineering. Nucleic Acids Res., 46:4152-4163, 2018 Cited by PubMed: 29635476DOI: 10.1093/nar/gky235 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.598 Å) |
Structure validation
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