6F4Q
Human JMJD5 (Q275C) in complex with Mn(II), NOG and RPS6-A138C (129-144) (complex-2)
6F4Q の概要
エントリーDOI | 10.2210/pdb6f4q/pdb |
関連するPDBエントリー | 6F4M 6F4N 6F4O 6F4P 6F4R 6F4S 6F4T |
分子名称 | JmjC domain-containing protein 5, 40S ribosomal protein S6, MANGANESE (II) ION, ... (7 entities in total) |
機能のキーワード | oxidoreductase, non-heme, iron, 2-oxoglutarate, dioxygenase, jmjc, jmjc domain, lysine-specific demethylase 8, jmjc domain-containing protein 5, arginyl c-3 hydroxylase, jmjd5, kdm8, oxygenase, hypoxia, dna-binding, metal-binding, translation, dsbh, facial triad, cytoplasm, jmjc hydroxylase, jmjc demethylase, kdms, post-translational modifications, ptm, beta-hydroxylation, hydroxylation, arginine hydroxylation, rcc1 domain-containing protein 1, rccd1, regulator of chromosome condensation, 40s ribosomal protein s6, rps6, ribosome biogenesis, transcription, epigenetic regulation, signaling, development, cell structure, transcription activator/inhibitor, phosphorylation, cancer, polymorphism |
由来する生物種 | Homo sapiens (Human) 詳細 |
細胞内の位置 | Nucleus : Q8N371 |
タンパク質・核酸の鎖数 | 2 |
化学式量合計 | 31899.91 |
構造登録者 | |
主引用文献 | Wilkins, S.E.,Islam, S.,Gannon, J.M.,Markolovic, S.,Hopkinson, R.J.,Ge, W.,Schofield, C.J.,Chowdhury, R. JMJD5 is a human arginyl C-3 hydroxylase. Nat Commun, 9:1180-1180, 2018 Cited by PubMed: 29563586DOI: 10.1038/s41467-018-03410-w 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (1.12 Å) |
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