6F4Q
Human JMJD5 (Q275C) in complex with Mn(II), NOG and RPS6-A138C (129-144) (complex-2)
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 5 |
Details | binding site for residue MN A 501 |
Chain | Residue |
A | HIS321 |
A | ASP323 |
A | HIS400 |
A | OGA502 |
A | HOH786 |
site_id | AC2 |
Number of Residues | 14 |
Details | binding site for residue OGA A 502 |
Chain | Residue |
A | ASP323 |
A | ASN327 |
A | LEU329 |
A | LYS336 |
A | HIS400 |
A | VAL402 |
A | SER412 |
A | TRP414 |
A | MN501 |
A | HOH764 |
A | TYR272 |
A | TRP310 |
A | SER318 |
A | HIS321 |
site_id | AC3 |
Number of Residues | 14 |
Details | binding site for residue TRS A 503 |
Chain | Residue |
A | LEU200 |
A | VAL201 |
A | GLY203 |
A | GLN326 |
A | TYR350 |
A | LYS372 |
A | PHE373 |
A | VAL396 |
A | HOH627 |
A | HOH636 |
A | HOH648 |
A | HOH685 |
A | HOH696 |
A | HOH865 |
site_id | AC4 |
Number of Residues | 6 |
Details | binding site for residue GOL A 504 |
Chain | Residue |
A | ARG196 |
A | ARG268 |
A | ASP269 |
A | SER296 |
A | LEU297 |
A | HOH630 |
site_id | AC5 |
Number of Residues | 7 |
Details | binding site for residue GOL A 505 |
Chain | Residue |
A | ARG189 |
A | PRO190 |
A | GLU266 |
A | ASP293 |
A | TYR294 |
A | HOH693 |
A | HOH720 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 1 |
Details | MOD_RES: (3R)-3-hydroxyarginine => ECO:0000269|PubMed:29563586 |
Chain | Residue | Details |
B | ARG137 | |
A | VAL237 | |
A | ASP280 |
site_id | SWS_FT_FI2 |
Number of Residues | 3 |
Details | BINDING: BINDING => ECO:0000269|PubMed:22851697, ECO:0000269|PubMed:29459673, ECO:0000269|PubMed:29563586, ECO:0000305|PubMed:24100311, ECO:0007744|PDB:3UYJ, ECO:0007744|PDB:4GJZ, ECO:0007744|PDB:4QU1, ECO:0007744|PDB:5FBJ |
Chain | Residue | Details |
A | THR234 | |
A | ILE289 | |
A | GLY298 |
site_id | SWS_FT_FI3 |
Number of Residues | 3 |
Details | BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00538, ECO:0000305|PubMed:22851697, ECO:0000305|PubMed:24100311, ECO:0007744|PDB:4GJY, ECO:0007744|PDB:4GJZ |
Chain | Residue | Details |
A | PRO283 | |
A | LEU285 | |
A | GLN362 |
site_id | SWS_FT_FI4 |
Number of Residues | 1 |
Details | BINDING: BINDING => ECO:0000269|PubMed:22851697, ECO:0000269|PubMed:29459673, ECO:0000269|PubMed:29563586, ECO:0007744|PDB:3UYJ, ECO:0007744|PDB:4GJZ |
Chain | Residue | Details |
A | PHE376 |