6F0W

prolyl hydroxylase in complex with hypoxia inducible factor oxygen degradation domain peptide fragment from Trichoplax adhaerens

Summary for 6F0W

Entry DOI	10.2210/pdb6f0w/pdb
Related	6YE1
Descriptor	HIF prolyl hydroxylase, Hypoxia inducible factor, alpha subunit, N-OXALYLGLYCINE, ... (5 entities in total)
Functional Keywords	prolyl hydroxylase, oxygenase, oxidoreductase, oxygen sensing, hypoxia inducible factor
Biological source	Trichoplax adhaerens (Trichoplax reptans) More
Total number of polymer chains	2
Total formula weight	31896.81
Authors	McDonough, M.A.,Boleininger, A.,Schofield, C.J. (deposition date: 2017-11-20, release date: 2018-10-03, Last modification date: 2024-01-17)
Primary citation	Lippl, K.,Boleininger, A.,McDonough, M.A.,Abboud, M.I.,Tarhonskaya, H.,Chowdhury, R.,Loenarz, C.,Schofield, C.J. Born to sense: biophysical analyses of the oxygen sensing prolyl hydroxylase from the simplest animal Trichoplax adhaerens. Hypoxia (Auckl), 6:57-71, 2018 Cited by PubMed: 30519597 DOI: 10.2147/HP.S174655 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.301 Å)

Structure validation