6F0W

prolyl hydroxylase in complex with hypoxia inducible factor oxygen degradation domain peptide fragment from Trichoplax adhaerens

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	HIF prolyl hydroxylase	polymer	257	29228.1	1	UniProt (I6QVT6) Pfam (PF13640)	Trichoplax adhaerens (Trichoplax reptans)
2	B (S)	Hypoxia inducible factor, alpha subunit	polymer	21	2466.7	1	UniProt (I6QP75) UniProt (by SIFTS) (B3RXX2)	Trichoplax adhaerens
3	C (A)	N-OXALYLGLYCINE	non-polymer		147.1	1	Chemie (OGA)
4	D (A)	MANGANESE (II) ION	non-polymer		54.9	1	Chemie (MN)
5	E, F (A, S)	water	water		18.0	200	Chemie (HOH)

Sequence modifications

A: 64 - 300 (UniProt: I6QVT6)

PDB	External Database	Details
Met 44	-	initiating methionine
Gly 45	-	expression tag
Ser 46	-	expression tag
Ser 47	-	expression tag
His 48	-	expression tag
His 49	-	expression tag
His 50	-	expression tag
His 51	-	expression tag
His 52	-	expression tag
His 53	-	expression tag
Ser 54	-	expression tag
Ser 55	-	expression tag
Gly 56	-	expression tag
Leu 57	-	expression tag
Val 58	-	expression tag
Pro 59	-	expression tag
Arg 60	-	expression tag
Gly 61	-	expression tag
Ser 62	-	expression tag
His 63	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	31694.8
Non-Polymers*	Number of molecules	2
	Total formula weight	202.0
All*	Total formula weight	31896.8

*Water molecules are not included.