6ERF
Complex of APLF factor and Ku heterodimer bound to DNA
Summary for 6ERF
Entry DOI | 10.2210/pdb6erf/pdb |
Descriptor | X-ray repair cross-complementing protein 6, X-ray repair cross-complementing protein 5, DNA (5'-D(*GP*TP*TP*TP*TP*TP*AP*GP*TP*TP*TP*AP*TP*TP*GP*GP*GP*CP*GP*CP*G)-3'), ... (6 entities in total) |
Functional Keywords | dna repair protein nhej, dna binding protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 20 |
Total formula weight | 588176.31 |
Authors | Nemoz, C.,Legrand, P.,Ropars, V.,Charbonnier, J.B. (deposition date: 2017-10-18, release date: 2018-10-17, Last modification date: 2024-01-17) |
Primary citation | Nemoz, C.,Ropars, V.,Frit, P.,Gontier, A.,Drevet, P.,Yu, J.,Guerois, R.,Pitois, A.,Comte, A.,Delteil, C.,Barboule, N.,Legrand, P.,Baconnais, S.,Yin, Y.,Tadi, S.,Barbet-Massin, E.,Berger, I.,Le Cam, E.,Modesti, M.,Rothenberg, E.,Calsou, P.,Charbonnier, J.B. XLF and APLF bind Ku80 at two remote sites to ensure DNA repair by non-homologous end joining. Nat.Struct.Mol.Biol., 25:971-980, 2018 Cited by PubMed: 30291363DOI: 10.1038/s41594-018-0133-6 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.01 Å) |
Structure validation
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