6EJ5
A conserved structural element in the RNA helicase UPF1 regulates its catalytic activity in an isoform-specific manner
Summary for 6EJ5
Entry DOI | 10.2210/pdb6ej5/pdb |
Descriptor | Regulator of nonsense transcripts 1 (2 entities in total) |
Functional Keywords | rna helicase, sf1 superfamily, nmd factor, rna binding protein |
Biological source | Homo sapiens (Human) |
Cellular location | Cytoplasm: Q92900 |
Total number of polymer chains | 1 |
Total formula weight | 71545.10 |
Authors | Gowravaram, M.,Bonneau, F.,Maciej, V.D.,Chakrabarti, S. (deposition date: 2017-09-20, release date: 2018-01-24, Last modification date: 2024-01-17) |
Primary citation | Gowravaram, M.,Bonneau, F.,Kanaan, J.,Maciej, V.D.,Fiorini, F.,Raj, S.,Croquette, V.,Le Hir, H.,Chakrabarti, S. A conserved structural element in the RNA helicase UPF1 regulates its catalytic activity in an isoform-specific manner. Nucleic Acids Res., 46:2648-2659, 2018 Cited by PubMed: 29378013DOI: 10.1093/nar/gky040 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.34 Å) |
Structure validation
Download full validation report