6EA5
Structure of BDBV GPcl in complex with the pan-ebolavirus mAb ADI-15878
Summary for 6EA5
Entry DOI | 10.2210/pdb6ea5/pdb |
Descriptor | Envelope glycoprotein, Glycoprotein, ADI-15878 Fab Heavy Chain, ... (7 entities in total) |
Functional Keywords | mab, gp, glycoprotein, ebola, ebov, antibody, bdbv, bundibugyo, neutralization, immune, bnab, complex, filovirus, viral protein, viral protein-immune system complex, viral protein/immune system |
Biological source | Bundibugyo ebolavirus More |
Total number of polymer chains | 12 |
Total formula weight | 236573.35 |
Authors | King, L.B.,West, B.R.,Moyer, C.L.,Fusco, M.L.,Milligan, J.C.,Hui, S.,Saphire, E.O. (deposition date: 2018-08-02, release date: 2018-09-19, Last modification date: 2023-10-11) |
Primary citation | West, B.R.,Moyer, C.L.,King, L.B.,Fusco, M.L.,Milligan, J.C.,Hui, S.,Saphire, E.O. Structural Basis of Pan-Ebolavirus Neutralization by a Human Antibody against a Conserved, yet Cryptic Epitope. MBio, 9:-, 2018 Cited by PubMed: 30206174DOI: 10.1128/mBio.01674-18 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (4.75 Å) |
Structure validation
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